Demodex: Beyond the Mite
Recurrence Biology and Ocular Surface Ecosystem Stability.
Course Overview
Demodex blepharitis is more than a mite infestation — it is a window into the ecology of the ocular surface. This Masterclass moves beyond the basics of Demodex identification and treatment to explore the biology of recurrence, the role of the ocular surface microbiome, and the conditions that allow Demodex to proliferate and persist. Understanding these dynamics is essential for achieving durable clinical outcomes rather than temporary suppression.
Clinical Relevance
With the approval of lotilaner ophthalmic solution, clinicians now have a targeted therapeutic option for Demodex blepharitis. But treatment success depends on more than eradication — it requires understanding why Demodex thrives in some patients, how to address the underlying conditions that promote recurrence, and how to counsel patients on long-term lid hygiene and ecosystem maintenance.
Course Details
Credit hours and COPE approval pending. Join the waitlist to receive notification when this course becomes available.
Learning Objectives
Upon successful completion of this educational experience, the clinician will be able to:
Describe the life cycle of Demodex folliculorum and Demodex brevis and their distinct clinical implications.
Explain the host and environmental factors that promote Demodex proliferation and recurrence.
Apply a systematic approach to the diagnosis of Demodex blepharitis, including the recognition of collarettes.
Select appropriate therapeutic strategies, including the role of lotilaner ophthalmic solution.
Develop a patient-centered management plan that addresses both acute treatment and long-term recurrence prevention.
Course Modules
This educational experience is organized into the following modules. Content is subject to refinement prior to final release.
Demodex Biology
Life cycle, species differences, and the ecological relationship between Demodex and the human host — understanding the organism to understand the disease.
Pathogenesis and Clinical Presentation
How Demodex causes disease — mechanical disruption, inflammatory mediators, and the clinical signs that distinguish Demodex blepharitis from other lid margin conditions.
The Ocular Surface Microbiome
The role of the lid margin microbiome in Demodex ecology — dysbiosis, host susceptibility, and the conditions that allow overgrowth.
Diagnosis
Clinical examination techniques, the significance of collarettes, and the role of ancillary evaluation in confirming Demodex infestation.
Therapeutic Strategies
Lotilaner ophthalmic solution, tea tree oil-based approaches, mechanical lid hygiene, and the evidence base for each — building a rational treatment plan.
Recurrence Prevention
Addressing the conditions that promote Demodex proliferation, patient education, and long-term management strategies for sustained ocular surface health.
Educational Philosophy
This educational experience is designed to support clinical reasoning and evidence-informed decision-making. It does not constitute clinical advice and should not replace consultation of official prescribing information, applicable standards of care, or the clinical judgment of the treating clinician. COPE approval and credit hours are pending and will be confirmed prior to release.
Be the First to Know
Join the waitlist for Demodex: Beyond the Mite and receive notification when this educational experience becomes available.
Companion Resource
The Clinician's Companion
Explore the therapeutic reference library designed to support the clinical reasoning developed in MYODCE educational experiences.
Explore the Companion